Features of Vitamin D Content in Chronic Viral Hepatitis C

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Role of vitamin D in chronic hepatitis C

Abbreviations: CHC, chronic hepatitis C; CYP, cytochrome P450; HCV, hepatitis C virus; IL, interleukin; Peg, pegylated interferon alfa; RBV, ribavirin; SVR, sustained virologic response; VDRs, vitamin D receptors; Th, helper T cell; 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)D, 1,25-dihydroxyvitamin D Corresponding author: Tae Yeob Kim Department of Internal Medicine, Hanyang University Guri Hospita...

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Vitamin D deficiency and vitamin D therapy in chronic hepatitis C.

BACKGROUND Vitamin D has immunomodulatory properties, exerts an anti-hepatitis C virus (HCV) effect in vitro and improves response to interferon-based therapy in patients with chronic hepatitis C (CHC). Low serum levels of 25(OH) vitamin D [25(OH)D] are frequently found in CHC patients and seem to be related to more advanced stages of liver fibrosis. The study aims to establish the incidence of...

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Vitamin D binding protein gene polymorphisms and baseline vitamin D levels as predictors of antiviral response in chronic hepatitis C.

UNLABELLED Vitamin D deficiency seems to predict the unsuccessful achievement of sustained viral response (SVR) after antiviral treatment in hepatitis C virus (HCV) difficult-to-treat genotypes. Vitamin D binding protein (GC) gene polymorphisms are known to influence vitamin D levels. This study was performed to assess whether the interaction between basal circulating vitamin D and the GC polym...

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Chronic viral hepatitis C: management update.

The management of chronic viral hepatitis C is evolving rapidly. Monotherapy with interferon, the accepted standard of treatment until recently, achieves only a modest sustained virological response rate of 15%. Combination treatment with alpha-2b interferon and ribavirin has been shown to increase sustained response rates to 40% in patients who have never been treated with interferon and to 50...

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Significance of Vitamin D Receptor Gene Polymorphisms for Risk of Hepatocellular Carcinoma in Chronic Hepatitis C

BACKGROUND/AIMS Biological and epidemiological data suggest that vitamin D levels may influence cancer development. Several single nucleotide polymorphisms have been described in the vitamin D receptor (VDR) gene in association with cancer risk. We aimed to investigate the association of VDR gene polymorphisms with hepatocellular carcinoma (HCC) development in chronic hepatitis C patients. ME...

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ژورنال

عنوان ژورنال: ACTUAL INFECTOLOGY

سال: 2017

ISSN: 2312-4148,2312-413X

DOI: 10.22141/2312-413x.4.13.2016.91456